Hematology

TTP is mediated by ADAMTS-13

New oral anticoagulant: dabigatran (Pradaxa) = direct thrombin inhibitor

Just to recap, with coumadin, we can measure PT/INR; for heparin, PTT; and for enoxaparin and its brood, (less rapidly) Factor Xa levels.

"Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran."

http://www.ncbi.nlm.nih.gov/pubmed/22227958